International Conference on Genome Biology and Host Defence: Bacteria to Mammals (GBHD-2019) will showcase and promote application of Next Gen sequencing and genomics technologies for basic and translational research in all areas of biology including human genetics, drug discovery, clinical medicine, biomarkers, diagnostics, animal, microbial, plant and agricultural sciences. It will also cover the topics on basic biology and the latest research on host defence. The conference is aimed at bringing together leading academic scientists and aspiring young researchers to exchange and share the most exciting developments in the fields of biological sciences, genome biology and host defence. The conference is planned to be held in Madurai one of the historical temple cities in South India, during February 27, 28 & March 1, 2019. It is envisaged that this conference would not only provide a unique platform to the participants from industries and academic institutions but also serve the purpose of global networking among them and help in creating a nucleus of interface research.